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. geology . astronomy . gender .
. graphic design . radical organizing .
. bemused eschatophile .
. white poly pansexual (gender)queer .
. they . them . theirs .
. apocalypse punx .
. music . food . people .

i'm also a co-manager of the
Folk Routes Distro Collective

 

mindblowingscience:

Researchers eliminate HIV from cultured human cells for first time

HIV-1, the most common type of the virus that causes AIDS,has proved to be tenacious, inserting its genome permanently into its victims’ DNA, forcing patients to take a lifelong drug regimen to control the virus and prevent a fresh attack. Now, a team of Temple University School of Medicine researchers has designed a way to snip out the integrated HIV-1 genes for good.

"This is one important step on the path toward a permanent cure for AIDS," says Kamel Khalili, PhD, Professor and Chair of the Department of Neuroscience at Temple. Khalili and his colleague, Wenhui Hu, MD, PhD, Associate Professor of Neuroscience at Temple, led the work which marks the first successful attempt to eliminate latent HIV-1 virus from human cells. "It’s an exciting discovery, but it’s not yet ready to go into the clinic. It’s a proof of concept that we’re moving in the right direction," added Dr. Khalili, who is also Director of the Center for Neurovirology and Director of the Comprehensive NeuroAIDS Center at Temple.
In a study published July 21 by theProceedings of the National Academy of Sciences, Khalili and colleagues detail how they created molecular tools to delete the HIV-1 proviral DNA. When deployed, a combination of a DNA-snipping enzyme called a nuclease and a targeting strand of RNA called a guide RNA (gRNA) hunt down the viral genome and excise the HIV-1 DNA. From there, the cell’s gene repair machinery takes over, soldering the loose ends of the genome back together — resulting in virus-free cells.
"Since HIV-1 is never cleared by the immune system, removal of the virus is required in order to cure the disease," says Khalili, whose research focuses on the neuropathogenesis of viral infections. The same technique could theoretically be used against a variety of viruses, he says.



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mindblowingscience:

Researchers eliminate HIV from cultured human cells for first time

HIV-1, the most common type of the virus that causes AIDS,has proved to be tenacious, inserting its genome permanently into its victims’ DNA, forcing patients to take a lifelong drug regimen to control the virus and prevent a fresh attack. Now, a team of Temple University School of Medicine researchers has designed a way to snip out the integrated HIV-1 genes for good.

"This is one important step on the path toward a permanent cure for AIDS," says Kamel Khalili, PhD, Professor and Chair of the Department of Neuroscience at Temple. Khalili and his colleague, Wenhui Hu, MD, PhD, Associate Professor of Neuroscience at Temple, led the work which marks the first successful attempt to eliminate latent HIV-1 virus from human cells. "It’s an exciting discovery, but it’s not yet ready to go into the clinic. It’s a proof of concept that we’re moving in the right direction," added Dr. Khalili, who is also Director of the Center for Neurovirology and Director of the Comprehensive NeuroAIDS Center at Temple.

In a study published July 21 by theProceedings of the National Academy of Sciences, Khalili and colleagues detail how they created molecular tools to delete the HIV-1 proviral DNA. When deployed, a combination of a DNA-snipping enzyme called a nuclease and a targeting strand of RNA called a guide RNA (gRNA) hunt down the viral genome and excise the HIV-1 DNA. From there, the cell’s gene repair machinery takes over, soldering the loose ends of the genome back together — resulting in virus-free cells.

"Since HIV-1 is never cleared by the immune system, removal of the virus is required in order to cure the disease," says Khalili, whose research focuses on the neuropathogenesis of viral infections. The same technique could theoretically be used against a variety of viruses, he says.

magictransistor:

Asa Smith. Celestial Illustrations from Smith’s Illustrated Astronomy. 1851. 

Wood engravings with hand highlighting, written by the principal of Public School No. 12 in New York City with the goal “to present all the distinguishing principles in physical Astronomy with as few words as possible”.

queenfattyoftherollpalace:

If children of color have to be aware of the realities of racism, white children should too.

I’m tired of hearing that white children are too young to understand the consequence of their words or actions when for nonwhite kids they live with the impact of racism every day 

kinomatika:

dumb lil comic about goats

theres a reason the rev didnt ever go into animal husbandry.

smithsonianlibraries:

Some days just call for unicorns and rainbows. Being one of those days, the only rainbow I could find was a rainbow slug snail. 

Unicorns from Johnston’s Historiae naturalis de quadrupetibus libri  
Rainbow snail from Cuvier’s Les mollusques : décrits et figurés d’après la classification


Self portrait and earth work by Ana Mendieta.
"I have been carrying on a dialogue between the landscape and the female body (based on my own silhouette)… I am overwhelmed by the feeling of having been cast from the womb (nature). Through my earth/body sculptures I become one with the earth… I become an extension of nature and nature becomes an extension of my body…" - Ana Mendieta

Self portrait and earth work by Ana Mendieta.

"I have been carrying on a dialogue between the landscape and the female body (based on my own silhouette)… I am overwhelmed by the feeling of having been cast from the womb (nature). Through my earth/body sculptures I become one with the earth… I become an extension of nature and nature becomes an extension of my body…" - Ana Mendieta

(Source: crystallizations)

republicx:

Photographer Kilian Schönberger created Brothers Grimm Homeland

German photographer Kilian Schönberger recently has presented his new project called “Brothers Grimm’s Homeland”, where author mixed photography with illustration. Big trees, dark homes and moody environment - these are the key elements that connected these photos with legendary Brother Grimm even more. Love it!

(Source: behance.net)